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- Moreover, a element of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity.
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Moreover, a element of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity. However, testosterone in physiologic doses might even be helpful in patients with angina , have greater ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood move in men with established coronary artery disease . Therefore, an interplay of endogenous elements of the patient’s risk profile as properly as the testosterone dosing may be issues of whether or not opposed events happen.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac threat factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient additionally had polycythemia, probably secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the proper coronary artery. Physicians and sufferers ought to concentrate on the clinical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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